{"api_version":"v1","slug":"pbs-proton-capsular-contracture-pmrt","name":"PBS Proton vs IMRT Capsular Contracture Post-Mastectomy","occurrence_count":1,"occurrences":[{"date":"2026-05-20","conference":null,"disease_site":"breast","study":{"name":"PBS Proton vs IMRT Capsular Contracture Post-Mastectomy","tldr":"PBS proton vs IMRT in post-mastectomy reconstruction: capsular contracture risk comparison; no effect size reported in source.","details":["🔍 Retrospective comparative study, post-mastectomy reconstruction setting, PBS proton vs IMRT","📊 Primary question: does PBS proton PMRT carry higher capsular contracture risk vs IMRT? No effect size reported in source","⚠️ Full text not available; no outcomes data extractable from citation alone","⚠️ Likely single-institution retrospective; PBS cohort selection bias plausible (proton pts may carry lower baseline reconstruction risk)","🔗 Capsular contracture is a recognized late toxicity endpoint in post-mastectomy RT; prior photon data suggest dose heterogeneity as a driver","❓ Whether PBS proton's sharper dose falloff translates to lower implant toxicity vs IMRT remains an open clinical question"],"key_figure_url":null,"key_figure_caption":null,"nct":null,"tweet_ids":[1000000006],"slug":"pbs-proton-capsular-contracture-pmrt","verdict":{"soc_implication":"unclear","rationale":"Citation only; no outcomes data in source. Cannot assess design validity, effect direction, or magnitude.","audience":"Post-mastectomy pts undergoing implant reconstruction, PMRT candidates"},"open_questions":["Does PBS proton reduce capsular contracture vs IMRT in implant reconstruction?","Is selection bias driving any observed difference in proton cohorts?"],"source_ids":[{"type":"paper","id":6}]}}]}